Since the first IVF baby was born in 1978, techniques have evolved considerably in vitro fertilization (IVF). Initially, with success rates in the single figures, IVF is now effective in about 50% of cases involving women under 35. Further, your chances of success increase when you choose the best IVF clinic in Jaipur.
As technology cannot ensure victory, some couples undergoing IVF therapy may experience failure despite numerous cycles, referred to as recurrent implantation failure. Moreover, it may be very financially and mentally exhausting when a couple cannot conceive despite their best efforts.
Implantation failure may be caused for many reasons, including embryonic causes, oocyte or sperm variables, or uterine factors. Additionally, the mother’s advanced age is a frequent factor since late marriage and pregnancy plans have been delayed. Other risk factors include obesity, smoking, anxiety, and an unhealthy lifestyle.
If IVF Failure is something that concerns you, then don’t worry. The leading IVF center in Jaipur offers IVF and other infertility treatments with the highest success rates. The holistic medical services by the clinic and the emotional support by Dr. Namita Kotia, IVF Specialist, and her team will improve the success rates of IVF and other treatments.
Despite numerous attempts, there may be chances that you are facing IVF failures experts who bring you some of the reasons for Recurrent IVF Failures.
The Reasons Behind Recurrent IVF Failures
While it is well known that women have a decreased probability of getting pregnant as they advance, a loss in egg quantity and quality also lowers the likelihood of a clinical pregnancy or live delivery after IVF therapy.
The laboratory phase of IVF therapy involves fertilizing the eggs and sperm to develop an embryo. Moreover, while embryos may seem healthy in the laboratory when transplanted into the uterus, they may fail to implant due to an undetectable abnormality.
In normal circumstances, an embryo enters the womb at the blastocyst stage. The blastocyst stage embryo has a greater implantation probability than the cleavage stage embryo due to the improved selection process.
Further, adding morphokinetics to the selection process will increase the success percentage. Preimplantation genetic screening (PGS) of the embryos will offer further details on the genetic normalcy of the embryos.
During the first stages of IVF therapy, the female must get daily injections of a fertility hormone known as follicle-stimulating hormone (FSH), which stimulates egg formation. Sometimes women’s ovaries may not react well to this medicine, and as a result, they do not generate enough eggs for retrieval. This is particularly true for older women, who already have a depleted egg supply (low ovarian reserve).
If there is a poor ovarian response, this does not indicate the IVF treatment is over. Examinations and medication adjustments may be necessary to rectify the issue. Blood samples for Anti-Mullerian Hormone (AMH) and ultrasound can determine the antra follicle level to help in determining the ovarian reserve.
The ovarian reserve would indicate the optimal protocol and amount of the hormone required to activate the ovaries and generate a sufficient number of eggs.
Some other reasons can include:
- Some previously diagnosed uterine abnormalities like uterine fibroid and endometrial polyps/septum may result in implantation failures.
- Poor Endometrium: Endometrium of poor quality, i.e., thin endometrium, is unsuitable for the implant.
- If the embryonic layer within the oocyte, referred to by the term zona, is thicker than expected, it can contribute to implantation failure. So this is because sperms cannot break the zone when fertilization occurs.
- Genetic Abnormalities in the Gametes: A defect of any kind, even the smallest ones such as chromosomal microdeletions, affects the quality of the gamete and, consequently, the embryo.
- Autoimmune Disorders: If you have an autoimmune disease that could put you susceptible to recurrent IVF failures. Usually, screening occurs in conjunction with repeated pregnancy losses to rule out autoimmune disorders.
- Other conditions like thyroid disorders, PCOD, uncontrolled diabetes, etc., can complicate pregnancy.
- The difficulty of embryo Transfer: One of the most common reasons for IVF process failures is embryo transfer. The challenges with embryo transfer or the sight of blood at the catheter’s tips suggest an increased risk of loss.
By consulting the best gynaecologist or treating your underlying condition, you can improve the chances of IVF success.
How Do You Avoid Repeated IVF Failure?
Here are some tips you can take to help prevent the possibility of IVF failures:
- You should first consider a thorough medical examination that involves an ultrasound scan and blood testing.
- Then, you can opt for a laparoscopic test to determine and address any physical obstructions in the conception.
- After that, your physician will decide and begin the appropriate treatment for you.
- Your doctor will ensure that your endometrium is suitable for implantation by assessing thickness and quality.
If you’re experiencing constant IVF failure, don’t be worried. There are many methods such as ICSI and IUI which can boost the process of IVF.
You must ensure you receive your treatment through an experience and the best IVF centre. Aastha Fertility has 15 years of experience 40-50 % success rate. The center offers ART services, including IVF, ICSI, and IUI. Get all solutions to your fertility problems with Aastha Fertility. Book a consultation today.